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Apexbio Technology LLC BHQ 88-58-4 100mg
SDP

Supplier:  Apexbio Technology LLC B6648100

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BHQ (2 5-di-tert-butyl-1 4-benzohydroquinone CAS 88-58-4) is a selective inhibitor of the endoplasmic reticulum Ca -ATPase which is responsible for transporting calcium from the cytosol into the sarcoplasmic or endoplasmic reticulum In rat basophilic leukemia cells 10 M BHQ inhibits inward rectifier potassium currents and may induce cell depolarization and affect calcium influx In vascular smooth muscle studies BHQ modulates calcium-induced contractions in a K -dependent manner and inhibits L-type calcium currents (IC 66 7 M) via superoxide anion generation In MDCK cells BHQ increases intracellular calcium in a dose-dependent manner (EC 40 M) by depleting ER calcium stores BHQ is widely used to investigate calcium signaling and ER function

Catalog No. 50-224-0408


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