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Medchemexpress LLC BI-0474 | 2750570-55-7 | 99.8% | 587.74 | 25 MG
Supplier: Medchemexpress LLC 25MGHY148278
BI-0474 is a potent KRASG12C inhibitor demonstrating significant activity against NCI-H358 cells with G12C mutations and anti-tumor effects in non-small cell lung cancer xenograft models.
- Potent KRASG12C inhibitor
- IC50 of 7.0 nM for GDP-KRAS::SOS1 protein-protein interaction
- Exhibits anti-proliferative activity against NCI-H358 cells with G12C mutation
- Demonstrates anti-tumor activity in non-small cell lung cancer xenograft models
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