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Medchemexpress LLC Bi-1347 | 2163056-91-3 | ≥98.0% | 1 ML
Supplier: Medchemexpress LLC HY12035010MM 1ML
Bi-1347 is a potent, selective small-molecule inhibitor of cyclin-dependent kinase 8 (CDK8), reported IC50 ≈ 1-1.1 nM. It has demonstrated antitumoral activity in preclinical models and is used as a research tool to probe CDK8/19 biology. Supplied as a 10 mM solution in DMSO for in vitro studies; research use only.
- Potent CDK8 inhibitor (IC50 ≈ 1-1.1 nM)
- Shows antitumoral activity in preclinical models
- Also active against CDK19 with high selectivity
- Provided as 10 mM solution in DMSO for in vitro experiments
- Intended for research use only; not for human therapeutic use
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