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Medchemexpress LLC BI 224436 | 1155419-89-8 | 99.7% | 442.51 | 50 MG
Supplier: Medchemexpress LLC HY1859550MG
BI 224436 is a novel HIV-1 noncatalytic site integrase inhibitor. It exhibits EC50 values of less than 15 nM against different HIV-1 laboratory strains. Originally designed by Boehringer Ingelheim, this compound is suitable for various laboratory research applications.
- Novel HIV-1 noncatalytic site integrase inhibitor
- Effective against different HIV-1 laboratory strains with EC50 values less than 15 nM
- Displays an additive effect in combination with most approved antiretrovirals
- Retains full antiviral activity against recombinant viruses encoding INSTI resistance substitutions
- Exhibits excellent pharmacokinetic profiles in rat, monkey, and dog
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