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Medchemexpress LLC BI-2493 | 2937344-16-4 | C24H27N7OS | 1 MG
Supplier: Medchemexpress LLC HY1537231MG
BI-2493 is a structural analogue of BI-2865, functioning as a highly selective and orally active pan-KRAS inhibitor. It is capable of attenuating tumor growth and is applicable for cancer disease research.
- Functions as a highly selective and orally active pan-KRAS inhibitor
- Attenuates tumor growth
- Used for cancer diseases research
- Inhibits the proliferation of KRAS mutant cancer cell lines in a concentration-dependent manner in vitro
- Exhibits tumor-suppressive activity in xenograft NMRI mice models in vivo
- Reduces tumor growth in mice carrying KRAS G12C, G12D, G12V, and A146V mutation models without significant toxicity
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