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Medchemexpress LLC BI-2545 | 2162961-71-7 | ≥98.0% | 527.4 g/mol | C23H19F6N5O3 | 100MG
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Supplier:  Medchemexpress LLC HY124772100MG

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BI-2545 is a research chemical probe that potently inhibits autotaxin (ATX) and lowers lysophosphatidic acid (LPA) levels in vivo. It is suitable for both in vitro and in vivo studies, shows selectivity in biochemical assays, and has documented whole-blood activity and favorable safety margins in preclinical profiling.

  • Potent ATX inhibition with human ATX IC50 ≈ 2.2 nM and rat ATX IC50 ≈ 3.4 nM.
  • Reduces LPA levels in vivo in animal studies.
  • Suitable for both in vitro and in vivo experimental use.
  • Demonstrated whole-blood activity (human ≈ 29 nM, rat ≈ 96 nM).
  • High chemical purity available (≥98.0%).
  • Molecular weight 527.4 g/mol; formula C23H19F6N5O3.

Catalog No. 50-002-37120


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