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Selleck Chemical LLC BI-2852 5mg

Supplier: Selleck Chemical LLC S89595MG

BI-2852 is a potent inhibitor ofKRAS that binds with nanomolar affinity to a pocket between switch I and II on RAS. BI-2852 blocks all GEF, GAP, and effector interactions with KRAS, leading to inhibition of downstream signaling and an antiproliferative effect in the low micromolar range in KRAS mutant cells. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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