Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000376872

Medchemexpress LLC BI-2865 | 2937327-93-8 | C23H27N7O2S | 1 ML
SDP

Supplier:  Medchemexpress LLC HY15372410MM/1ML

Encompass_Preferred

BI-2865 is a non-covalent pan-KRAS Inhibitor. It binds to wild-type and various mutant KRAS forms, including G12C, G12D, G12V, and G13D, inhibiting the proliferation of mutant KRAS expressing BaF3 cells. Characterized by a prolinol substituent and a pyrimidine linker, it forms specific interactions within the KRAS binding site. This product is for research use only.

  • Binds to wild-type and various mutant KRAS forms
  • Inhibits proliferation of mutant KRAS expressing BaF3 cells
  • Features a prolinol substituent and a pyrimidine linker
  • Demonstrates direct ionic interaction with E62
  • Forms a water-mediated hydrogen bond network with R68 and Q61

Catalog No. 50-003-76872


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.