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Medchemexpress LLC BI-2865 | 2937327-93-8 | C23H27N7O2S | 100 MG
SDP

Supplier:  Medchemexpress LLC HY153724100MG

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BI-2865 is a non-covalent pan-KRAS Inhibitor. It binds to WT, G12C, G12D, G12V, and G13D mutant KRAS. It inhibits the proliferation of G12C, G12D, or G12V mutant KRAS expressing BaF3 cells (mean IC50: approximately 140 nM). This derivative features a prolinol substituent and a pyrimidine linker.

  • Binds to various mutant KRAS forms
  • Inhibits proliferation of mutant KRAS expressing cells
  • Features a prolinol substituent
  • Includes a pyrimidine linker

Catalog No. 50-003-76021


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