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TARGETMOL CHEMICALS INC BI-2865 5MG

Supplier: TARGETMOL CHEMICALS INC T720625MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. BI-2865 is a non-covalent pan-KRAS inhibitor.BI-2865 binds to KRAS WT G12C G12D G12V and G13D mutants with KD values of 6.9 4.5 32 26 and 4.3 nM respectively.BI-2865 showed antiproliferative activity in BaF3 cells expressing KRAS G12C G12D or G12V mutants. BI-2865 showed antiproliferative activity on BaF3 cells expressing KRAS G12C G12D or G12V mutants with an average IC50 value of approximately 140 nM. purity: 99%
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