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Medchemexpress LLC BI-3231 | 2894848-07-6 | 99.8% | 380.37 | 50 MG
SDP

Catalog No. 5000361501
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BI-3231 is a potent and selective chemical probe that inhibits hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), with IC50 values of 1 nM for hHSD17B13 and 13 nM for mHSD17B13. It is being researched for its potential in treating nonalcoholic steatohepatitis (NASH) and other liver diseases.

  • Potent and selective hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) inhibitor
  • Demonstrates high metabolic stability in liver microsomes
  • Moderate metabolic stability in hepatocytes
  • Significant hepatic exposure maintained over 48 hours
  • Potential for research into nonalcoholic steatohepatitis (NASH) and other liver diseases
  • Powder storage: -20°C for 3 years
  • In solvent storage: -80°C for 6 months, -20°C for 1 month
  • Solubility in DMSO: 125 mg/mL (328.63 mM)

Catalog No. 50-003-61501 Supplier Medchemexpress LLC Supplier No. HY14881450MG
May include imposed supplier surcharges.
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BI-3231 is a potent and selective chemical probe that inhibits hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), with IC50 values of 1 nM for hHSD17B13 and 13 nM for mHSD17B13. It is being researched for its potential in treating nonalcoholic steatohepatitis (NASH) and other liver diseases.

  • Potent and selective hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) inhibitor
  • Demonstrates high metabolic stability in liver microsomes
  • Moderate metabolic stability in hepatocytes
  • Significant hepatic exposure maintained over 48 hours
  • Potential for research into nonalcoholic steatohepatitis (NASH) and other liver diseases
  • Powder storage: -20°C for 3 years
  • In solvent storage: -80°C for 6 months, -20°C for 1 month
  • Solubility in DMSO: 125 mg/mL (328.63 mM)

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