Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC BI-3406 | 2230836-55-0 | 99.95% | 462.46 | 10 MG
Supplier: Medchemexpress LLC 10MGHY125817
BI-3406 is an orally active, highly potent, and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1). It potently reduces the formation of GTP-loaded KRAS and inhibits MAPK pathway signaling, exhibiting anticancer activity. This compound shows activity on a broad panel of KRAS oncogenic variants, including all major G12 and G13 oncoproteins, and effectively limits cell proliferation in KRAS G12 or G13 mutant cells.
- Highly potent and selective inhibitor of KRAS-SOS1 interaction
- Reduces formation of GTP-loaded KRAS
- Inhibits MAPK pathway signaling
- Exhibits anticancer activity
- Active against a broad panel of KRAS oncogenic variants (G12 and G13)
- Limits cell proliferation in KRAS G12 or G13 mutant cells
- Available for research use only
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?