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Medchemexpress LLC BI-3663 | 2341740-84-7 | 99.84% | 917.84 | 1 ML
Supplier: Medchemexpress LLC HY111546100MG
BI-3663 is a highly selective PTK2/FAK PROTAC that hijacks E3 ligases for PTK2 degradation using Cereblon ligands. It inhibits PTK2 with an IC50 of 18 nM. This PROTAC is formed by linking BI-4464 to Pomalidomide. It exhibits anti-cancer activity and potently degrades PTK2 in Hep3B2.1-7 and A549 cells.
- Highly selective PTK2/FAK PROTAC.
- Inhibits PTK2 with an IC50 of 18 nM.
- Utilizes Cereblon ligands for E3 ligase hijacking and PTK2 degradation.
- Exhibits anti-cancer activity.
- Potently degrades PTK2 in Hep3B2.1-7 and A549 cells.
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