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Apexbio Technology LLC BI-9564 1883429-22-8 50mg
Supplier: Apexbio Technology LLC B618450
BI-9564 (CAS 1883429-22-8) is a small molecule inhibitor selective for the bromodomains BRD9 and BRD7 two structurally related proteins involved in chromatin remodeling BI-9564 demonstrates inhibitory potency with an IC50 of 75 nM for BRD9 and 3 4 M for BRD7 showing higher affinity for BRD9 The compound exhibits minimal off-target activity against BET family proteins In vivo oral administration of BI-9564 in murine tumor xenograft models significantly suppresses tumor growth BI-9564 is widely used in preclinical research to study the biological roles of BRD9/7 in cancer and epigenetic modulation pathways
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