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Selleck Chemical LLC BI-D1870 S2843-1g

Supplier: Selleck Chemical LLC S28431G
BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM in cell-free assays respectively 10- to 100-fold selectivity for RSK than MST2 GSK-3 MARK3 CK1 and Aurora B BI-D1870 exhibits anticancer attributes including the generation of reactive oxygen species (ROS) and increases in endoplasmic reticulum (ER) stress and autophagy
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