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Enzo Life Sciences BI-D1870, (1mg), CAS Number: 501437-28-1
SDP

Supplier:  Enzo Life Sciences BMLEI4070001

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S6 kinase inhibitor. Cell permeable, ATP-competitive inhibitor of the four isoforms of ribosomal S6 kinase (p90 RSK) (IC50's at 100µM ATP: RSK1 = 31nM, RSK2 = 24nM, RSK3 = 18nM, RSK4 = 15nM). Does not significantly inhibit 10 other AGC kinases, and over 40 other protein kinases at 100X concentrations. Acts on the N-terminal AGC kinase domain. Completely prevents PMA-induced TSC2 phosphorylation. Alternative Name: 2-[(3,5-Difluoro-4-hydroxyphenyl)amino]-7,8-dihydro-5,7-dimethyl-8-(3-methylbutyl)-6(5H)-pteridone. Formula: C19H23F2N5O2. MW: 391.4. CAS Number: 501437-28-1. Purity: ≥98% (HPLC). Appearance: Off-white solid. Solubility: Soluble in DMSO (>25mg/ml). Use/Stability: Stable for at least one year from the date of receipt when stored as supplied at -20°C. Long Term Storage: -20°C

Catalog No. NC0692760


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