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Cayman Chemical BIlIrubIn Stndard 1ea

Supplier: Cayman Chemical 4007781 EA

A mGluR1 allosteric antagonist (IC50 2.6 nM in CHO cells expressing the human receptor) is selective for mGluR1 over mGluR5 by 2000-fold as well as mGluR2 -4 -6 -7 or -8 at 10 UM in CHO cells expressing the human receptors reduces methamphetamine-induced hyperlocomotion in mice at 1-10 mg/kg p.o.
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