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Medchemexpress LLC Bimatoprost | 155206-00-1 | 99.9% | 100 MG
Supplier: Medchemexpress LLC HYB0191100MG
Bimatoprost is a prostaglandin analog that reduces intraocular pressure by regulating scleral and trabecular outflow. It is used in the study of open-angle glaucoma, ocular hypertension, and other forms of glaucoma. Topical application of bimatoprost can induce fat atrophy and cause a deepening of the eyelid sulcus. In vitro studies show that Bimatoprost dose-dependently upregulates the mRNA levels of cellular matrix metalloproteinases MMP1 and MMP14 in human trabecular meshwork (TM), iris fibroblasts (SF), and ciliary muscle (CM) cells.
- Reduces intraocular pressure
- Regulates scleral and trabecular outflow
- Suitable for study of open-angle glaucoma and ocular hypertension
- Upregulates mRNA of cellular matrix metalloproteinases MMP1 and MMP14 in TM, SF, and CM cells
- IOP response dependent on FP receptor expression
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