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Cayman Chemical BImIralIsIb 10mg
Supplier: Cayman Chemical 2344110 MG
A pan inhibitor of PI3Ks and an inhibitor of mTOR (IC50s = 33, 661, 708, 451, and 89 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, and mTOR, respectively); selective for these kinases over a panel of cell surface and nuclear receptors, membrane channels, transporters, kinases, proteases, and phosphodiesterases at a concentration of 10 μM; has anticancer activity (average GI50 = 0.7 μM across the NCI 60 human cancer cell line panel); reduces tumor growth in a dose-dependent manner in a PC3 prostate cancer mouse xenograft model
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