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Medchemexpress LLC Bio-AMS TFA | 1393881-52-1 | 98.0% | 685.65 | 1 MG
SDP

Supplier:  Medchemexpress LLC HY115448A1MG

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Bio-AMS (TFA) is a potent bacterial biotin protein ligase inhibitor. It exhibits selective activity against *Mycobacterium tuberculosis* (Mtb) and hinders fatty acid and lipid biosynthesis. It is for research use only and not sold to patients.

  • Potent bacterial biotin protein ligase inhibitor.
  • Selective activity against *Mycobacterium tuberculosis* (Mtb).
  • Arrests fatty acid and lipid biosynthesis.
  • Excellent antitubercular activity against Mtb H37Rv and MDR/XDR-TB strains with MICs ranging from 0.16 to 0.625 μM.
  • Its activity is not affected by changes to the primary carbon source.
  • Inhibits growth of Mtb in Mtb-infected mouse macrophages in a concentration-dependent manner (2.5, 5 and 10 μM; 24 h).
  • Shows no signs of mitochondrial toxicity.

Catalog No. 50-004-37788


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