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Bio X Cell RecombiMAb Anti-Mouse PD-L1, Clone 10F.9G2-CP154, 1 MG
Supplier: Bio X Cell CP154R001MG
The 10F.9G2™-CP154 monoclonal antibody is a recombinant chimeric version of the original 10F.9G2™ antibody, with variable domain sequences identical to the original but constant region sequences switched from rat IgG2b to mouse IgG2a. This antibody contains a LALA-PG mutation in the Fc fragment, preventing it from binding to endogenous Fcγ receptors. It reacts with mouse PD-L1 (programmed death ligand 1), also known as B7-H1 or CD274, and blocks its interaction with PD-1 and B7-1 (CD80).
- Recombinant chimeric antibody
- LALA-PG mutation in Fc fragment prevents binding to endogenous Fcγ receptors
- Blocks interaction between PD-L1 and PD-1, and between PD-L1 and B7-1 (CD80)
- Purified from CHO cell supernatant in an animal-free facility
- Purity ≥95%, determined by SDS-PAGE
- Endotoxin ≤0.5 EU/mg
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