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Apexbio Technology LLC Biochanin A 491-80-5 10mM (in 1mL DMSO)
SDP

Supplier:  Apexbio Technology LLC N13085.1

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Biochanin A (CAS number 491-80-5) is a naturally derived inhibitor of fatty acid amide hydrolase (FAAH) an enzyme responsible for metabolizing the endocannabinoid anandamide (AEA) In vitro studies show Biochanin A inhibits FAAH-mediated hydrolysis of AEA with IC50 values of 1 8 M (mouse) 1 4 M (rat) and 2 4 M (human) without affecting CB1 CB2 receptors or FAAH-2 In animal models Biochanin A attenuates formalin-induced phosphorylation of spinal extracellular signal-regulated kinase an effect reversible by CB1 receptor antagonist AM251 Biochanin A thus serves as a useful tool compound in pain regulation and endocannabinoid research

Catalog No. 50-000-62701


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