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FOCUS BIOMOLECULES Biochemical Reagents, C2230, Cav2.2 channel blocker, CAS 882243-88-1, 98% by TLC/NMR (Conforms)
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Biochemical Reagents, C2230, Cav2.2 channel blocker, CAS 882243-88-1, 98% by TLC/NMR (Conforms), C2230 is a novel Cav2.2 channel blocker (IC50 1.3 uM at -50 mV/ 10.2 uM at -80 mV) with a unique binding mode (no GPCR-mediated inhibition). It displays preferential binding to the inactive state of the channel. C2230 is active in both rat and human DRG neurons. Active in rat models of neuropathic pain and mouse models of osteoarthritis. C2230 does not affect somatosensation or motor and cardiac function.

Catalog No. NC3797292


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