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FOCUS BIOMOLECULES Biochemical Reagents, Mito-lonidamine, Mitochondria-targeted antiglycolytic agent, CAS 2361564-49-8, 98% by TLC/NMR (Conforms)
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Biochemical Reagents, Mito-lonidamine, Mitochondria-targeted antiglycolytic agent, CAS 2361564-49-8, 98% by TLC/NMR (Conforms), Antiglycolytic drug with limited efficacy.1,2 Mito-lonidamine (2361564-49-8) is lonidamine conjugated to a triphenylphosphonium moiety via a decyl-linker which is an effective mitochondria-targeting group.3 Mito-lonidamine was shown to be100-fold more potent than lonidamine. It is a tumor-selective inhibitor of oxidative phosphorylation inhibiting mitochondrial bioenergetics in lung cancer cells and suppressing lung cancer cell viability, growth, progression and metastasis of lung cancer xenografts in mice.3

Catalog No. NC3802713


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