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Medchemexpress LLC Biotin-COG1410 TFA | 98.0% | 1 MG
Supplier: Medchemexpress LLC HYP2136F1MG
Biotin-COG1410 TFA is a biotin-labeled COG1410. COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. It exerts neuroprotective and anti-inflammatory effects in a murine model of traumatic brain injury (TBI) and can be used for the research of neurological diseases.
- Decreases the production and release of NO and TNFα in BV2 microglia cells.
- Exhibits significant improvement on vestibulomotor function and spatial learning and memory in mice.
- Improves vestibulomotor function, decreases poststroke locomotor asymmetry, and decreases infarct volume of the ipsilateral hemisphere in rats.
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