Medchemexpress LLC Biotin-PEG4-amide-Alkyne | 1006592-45-5 | 96.41% | C24H40N4O7S | 100 MG

Supplier:  Medchemexpress LLC HY140923100MG

Biotin-PEG4-amide-Alkyne is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that enables it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups. PROTACs themselves are compounds that feature two distinct ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a specific protein of interest. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.

• Can be used in the synthesis of PROTACs.
• Functions as a click chemistry reagent.
• Contains an alkyne group.
• Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
• Allows for selective degradation of target proteins.

Catalog No. 50-003-54881