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Medchemexpress LLC Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide | 2599839-59-3 | MFCD00137487 | 95.0% | C47H67N9O10SSi | 10MG
Supplier: Medchemexpress LLC HY14538310MG
A clickable, acid-cleavable biotinylated PEG4 azide designed as an enrichment handle for labeling and enriching cell-surface glycoproteins. It incorporates a picolyl azide for efficient bioorthogonal conjugation and a dialkoxydiphenylsilane linker that permits acid-triggered release following affinity capture, providing a workflow for selective labeling, capture, and release of target biomolecules.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) for covalent labeling.
- Compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) for copper-free reactions.
- Acid-cleavable dialkoxydiphenylsilane linker allows release after enrichment.
- PEG4 spacer improves solubility and reduces steric hindrance.
- Biotin enables strong affinity capture with streptavidin reagents.
- Supplied with typical purity of 95% for consistent labeling results.
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