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ABclonal Technology Biotin Rabbit anti-Human CD40
SDP

Catalog No. 5000012811
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This gene belongs to the TNF-receptor superfamily and encodes a receptor on antigen-presenting cells crucial for mediating immune and inflammatory responses including T cell-dependent immunoglobulin class switching memory B cell development and germinal center formation The AT-hook transcription factor AKNA regulates both the receptor and its ligand important for homotypic cell interactions Adaptor protein TNFR2 mediates signal transduction by interacting with the receptor The receptor-ligand interaction is necessary for amyloid-beta-induced microglial activation playing a role in Alzheimer s disease Mutations in this gene cause autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3) Multiple alternatively spliced transcript variants encode distinct isoforms

Catalog No. 50-000-12811 Supplier ABclonal Technology Supplier No. A25703500T
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This gene belongs to the TNF-receptor superfamily and encodes a receptor on antigen-presenting cells crucial for mediating immune and inflammatory responses including T cell-dependent immunoglobulin class switching memory B cell development and germinal center formation The AT-hook transcription factor AKNA regulates both the receptor and its ligand important for homotypic cell interactions Adaptor protein TNFR2 mediates signal transduction by interacting with the receptor The receptor-ligand interaction is necessary for amyloid-beta-induced microglial activation playing a role in Alzheimer s disease Mutations in this gene cause autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3) Multiple alternatively spliced transcript variants encode distinct isoforms

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