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Sigma Aldrich Biotin-Slf

Catalog No. 9142235MG Shop All MilliporeSigma Sigma Organic Chemistry Products
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91-422-35MG 50 mg
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Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

Biotin-SLF (bio-SLF) is an FKBP12WT affinity probe useful in chemical biology or targeted protein degradation where FKBP12 is used as a tool protein and its enrichment is required in discovery experiments or assay validation.Related tools:Additional bifunctional tools for FKPB12 variants: dTAG-13 (SML2601) for FKBP12F36V; and KB02-SLF (914738), KB03-SLF (914975), and KB04-SLF (913715) for FKBP12WTCereblon (CRBN) affinity probe: Biotin-Thalidomide (913979)The dTAG system for immediate and target-specific protein degradationTechnology Spotlight: Building PROTAC™ Degraders for Targeted Protein DegradationPROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Specifications

CAS 2244085-89-8
Molecular Formula C33H54FN5O8 -+ xHCl
Linear Formula C12H20Cl2N2
MDL Number MFCD29075589
Quantity 50 mg
Synonym AVP conjugate for IAP-mediated protein degrader development; Ethyl (S)-2-((S)-1-((2S,5S)-17-amino-2-(tert-butyl)-5-methyl-4-oxo-9,12,15-trioxa-3,6-diazaheptadecanoyl)pyrrolidine-2-carboxamido)-3-(4-fluorophenyl)propanoate hydrochloride; SNIPER building block
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