Medchemexpress LLC Biotinylated covalent Btk inhibitor (CC-292) | 1202758-21-1 | 99.9% | 961.18 g/mol | C48H68N10O9S | 5 MG

Supplier:  Medchemexpress LLC HY1003385MG

CNX-500 is a biotinylated covalent probe created by linking a covalent Btk inhibitor to biotin. It retains potent inhibitory activity against Bruton's tyrosine kinase (Btk) with an IC50 of 0.5 nM and is intended for biochemical and cellular target engagement, labeling, and affinity-capture workflows.

• Covalent binding to Btk enabling irreversible target labeling.
• Biotin tag for affinity capture and pulldown experiments.
• High potency (Btk IC50 = 0.5 nM) for sensitive detection of engagement.
• High purity (>99.8%) suitable for research applications.
• Soluble in DMSO at 100 mg/mL; formulations reported for in vivo dosing.
• Stable as powder when stored at -20°C for long-term storage.

Catalog No. 50-002-14673