Sigma Aldrich Fine Chemicals Biosciences BioTracker Green Copper Li

Supplier:  Sigma Aldrich Fine Chemicals Biosciences SCT041

Copper is one of the trace metals required by living organisms and is an essential cofactor for enzyme activities of cytochrome c oxidase superoxide dismutase and tyrosinase. On the other hand abnormal homeostasis of copper leads to severe disorders such as Menkes syndrome and Wilsons disease or may be related to Alzheimers disease and cancers.BioTracker Green Copper Live Cell Dye is a fluorescent probe to detect Cu which is a dominant redox state of copper in an intracellular reducing environment. The dye is a colorless material with almost no fluorescence. Upon the reaction with Cu its fluorescence intensity at 510 nm increases more than 100 times to that before the reaction. However fluorescence increase is not observed in the presence of reactive oxygen species and other trace metals in cells including Cu2 Mn2 Co2 Ni2 fe fe2 and Zn2.Spectral PropertiesAbsorbance (max) 480nmEmission (max) 510nmResearch CategoryLive Cell Dye

Catalog No. 50-290-6511