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Selleck Chemical LLC Doramapimod (BIRB 796) 5mg 285983-48-4
Supplier: Selleck Chemical LLC S15745MG
Doramapimod (BIRB 796) is a pan-p38 MAPK inhibitor with IC50 of 38 nM, 65 nM, 200 nM and 520 nM for p38?/?/?/? in cell-free assays, and binds p38? with Kd of 0.1 nM in THP-1 cells, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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