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AdipoGen Bisindolylmaleimide I . hydrochloride [GF-109203X; G? 6850]

Supplier: AdipoGen AGCR10110M001
Bisindolylmaleimide I . hydrochloride [GF-109203X; G? 6850], AdipoGen Life Sciences. Chemical. CAS: 176504-36-2. Formula: C25H24N4O2 . HCl. MW: 412.5 . 36.5. Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM). Competitive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Necrosis inhibitor. Blocks hERG potassium channels. Promotes osteoblastogenesis in human mesenchymal stem cells.
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