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Abcam Bisindolylmaleimide II, PKC inhibitor, 5MG

Supplier:  Abcam AB1442065MG

Encompass_Preferred

MW 438.5 Da, Purity >97%. Potent, selective ATP-competitive PKC inhibitor (IC₅₀ values are 0.01, 0.75 and 2 μM for PKC, phosphorylase kinase and PKA respectively). Potent noncompetitive nAChR antagonist (IC₅₀ = 0.03 μM, catecholamine secretion in nicotine-stimulated PC-12 cells). Shows more potent antinicotinic effects than Bisindolylmaleimide IV (ab144208) and V (ab144205). Induces apoptosis and shows antiproliferative effects.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-270-5992


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