Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Indoles and derivatives
  7. Bisindolylmaleimide II, Tocris Bioscience™ 

Bisindolylmaleimide II, Tocris Bioscience™

Catalog Number p-4816577
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
137592-45-1
C27H26N4O2
438.531
LBFDERUQORUFIN-UHFFFAOYSA-N
bisindolylmaleimide ii, 2-1-2-1-methylpyrrolidino ethyl-1h-indol-3-yl-3-1h-indol-3-yl maleimide, bisindolyl deriv. 22, bim-2, bisindolylmaleimide ii mixture of 2 isomers, 3-1h-indol-3-yl-4-1-2-1-methylpyrrolidin-2-yl ethyl indol-3-yl pyrrole-2,5-dione, 3-1h-indol-3-yl-4-1-2-1-methyl-2-pyrrolidinyl ethyl-1h-indol-3-yl-1h-pyrrole-2,5-dione, 3-1h-indol-3-yl-4-1-2-1-methylpyrrolidin-2-yl ethyl-1h-indol-3-yl-2,5-dihydro-1h-pyrrole-2,5-dione, 3-1h-indol-3-yl-4-1-2-1-methylpyrrolidin-2-yl ethyl indol-3-yl-1h-pyrrole-2,5-dione
2397
3-(1H-indol-3-yl)-4-[1-[2-(1-methylpyrrolidin-2-yl)ethyl]indol-3-yl]pyrrole-2,5-dione
CN1CCCC1CCN2C=C(C3=CC=CC=C32)C4=C(C(=O)NC4=O)C5=CNC6=CC=CC=C65
This item is not returnable. View return policy
137592-45-1
C27H26N4O2
438.531
LBFDERUQORUFIN-UHFFFAOYSA-N
bisindolylmaleimide ii, 2-1-2-1-methylpyrrolidino ethyl-1h-indol-3-yl-3-1h-indol-3-yl maleimide, bisindolyl deriv. 22, bim-2, bisindolylmaleimide ii mixture of 2 isomers, 3-1h-indol-3-yl-4-1-2-1-methylpyrrolidin-2-yl ethyl indol-3-yl pyrrole-2,5-dione, 3-1h-indol-3-yl-4-1-2-1-methyl-2-pyrrolidinyl ethyl-1h-indol-3-yl-1h-pyrrole-2,5-dione, 3-1h-indol-3-yl-4-1-2-1-methylpyrrolidin-2-yl ethyl-1h-indol-3-yl-2,5-dihydro-1h-pyrrole-2,5-dione, 3-1h-indol-3-yl-4-1-2-1-methylpyrrolidin-2-yl ethyl indol-3-yl-1h-pyrrole-2,5-dione
2397
3-(1H-indol-3-yl)-4-[1-[2-(1-methylpyrrolidin-2-yl)ethyl]indol-3-yl]pyrrole-2,5-dione
CN1CCCC1CCN2C=C(C3=CC=CC=C32)C4=C(C(=O)NC4=O)C5=CNC6=CC=CC=C65

Description

Potent PKC inhibitor and nicotinic receptor antagonist

Potent, ATP-competitive protein kinase C (PKC) inhibitor (IC50 = 0.01 μM). Displays selectivity for PKC over protein kinase A (PKA) and phosphorylase kinase (PK) (IC50 values are 0.75 and 2μM for PK and PKA respectively). Also displays potent, noncompetitive antagonism at nicotinic cholinergic receptors (IC50 ∽ 0.03 μM for inhibition of catecholamine secretion in nicotine-stimulated PC-12 cells).
Quantity 10 mg
Formula Weight 438.52
Percent Purity >97%
Chemical Name or Material Bisindolylmaleimide II

Safety and Handling

Recommended Storage Store at -20°C
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit