Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Apexbio Technology LLC (-)-Blebbistatin 856925-71-8 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B13875.1
(-)-Blebbistatin is a cell-permeable small molecule inhibitor targeting non-muscle myosin II (NM II) an actin-dependent motor protein involved in cell adhesion migration and differentiation It selectively binds the myosin-ADP-phosphate complex slowing phosphate release and thereby suppressing Mg-ATPase and contractile activities mediated by actomyosin interactions It exhibits inhibitory potency in various model systems (IC50 0 5 5 0 M) with minimal effects on myosin isoforms I V X and reduced activity toward smooth muscle myosin II (IC50 80 M) Its reversible modulation of NM II renders it useful in research on cytoskeletal dynamics cell mechanics and related pathophysiological conditions
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?