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Medchemexpress LLC Bleomycin (sulfate) | 9041-93-4 | 99.49% | 1523 (average) | 100 MG
Supplier: Medchemexpress LLC HY17565100MG
Bleomycin sulfate is a DNA synthesis inhibitor and an antitumor antibiotic. It acts as a DNA damaging agent, causing single and double strand breaks and single apurinic/apyrimidinic sites in DNA. This radiomimetic compound is used to induce pulmonary fibrosis models and is rapidly absorbed with high bioavailability.
- DNA synthesis inhibitor
- Antitumor antibiotic
- Radiomimetic compound, resembling the genetic effect of ionizing radiation
- Causes single and double strand breaks and single apurinic/apyrimidinic sites in DNA
- Can be used to induce pulmonary fibrosis models
- Rapidly absorbed after intramuscular, subcutaneous, intraperitoneal, or intrapleural administration
- Reaches peak plasma concentrations in approximately 60 minutes
- Less than 1% binds to plasma proteins
- High bioavailability
- Mean plasma clearance rate of about 70 mL/min/m2
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