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Medchemexpress LLC Bleximenib oxalate | 2866179-95-3 | 98.0% | 689.82 | 1 MG
Supplier: Medchemexpress LLC HY148669A1MG
Bleximenib oxalate is an orally active and selective menin-KMT2A inhibitor with IC50 values of 0.1 nM, 0.045 nM, and ≤0.066 nM for humans, mice, and dogs, respectively. It can inhibit the proliferation and induce apoptosis and differentiation of tumor cells, making it suitable for research into tumors such as leukemia.
- Orally active and selective menin-KMT2A inhibitor
- Inhibits proliferation and induces apoptosis and differentiation of tumor cells
- Reduces expression of MEIS1, PBX3, FLT3, and JMJD1C
- Exhibits anti-tumor activity in mouse models of leukemia
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