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Medchemexpress LLC Bleximenib (oxalate) | 2866179-95-3 | 98.0% | 689.82 | 50 MG
Supplier: Medchemexpress LLC HY148669A50MG
Bleximenib oxalate is an orally active and selective menin-KMT2A inhibitor with IC50 values of 0.1 nM, 0.045 nM, and ≤0.066 nM for humans, mice, and dogs, respectively. It can inhibit the proliferation and induce apoptosis and differentiation of tumor cells and can be used in the research of tumors such as leukemia.
- Orally active and selective menin-KMT2A inhibitor
- Inhibits proliferation of tumor cells
- Induces apoptosis of tumor cells
- Induces differentiation of tumor cells
- Exhibits anti-tumor activity in mouse models of leukemia
- Increases the lifespan of mice in leukemia models
- Increases the expression of differentiation markers
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