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Medchemexpress LLC BLU-945 | 2660250-10-0 | 99.4% | C28H37FN6O3S | 100 MG
Supplier: Medchemexpress LLC HY144680100MG
BLU-945 is a potent, highly selective, reversible, and orally active epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). It effectively inhibits EGFR with L858R and/or exon 19 deletion mutation, T790M mutation, and C797S mutation, making it suitable for research into lung cancer, including non-small cell lung cancer (NSCLC).
- Potent, highly selective, reversible, and orally active EGFR tyrosine kinase inhibitor.
- Effectively inhibits EGFR with L858R and/or exon 19 deletion mutation, T790M mutation, and C797S mutation.
- Used for research of lung cancer, including non-small cell lung cancer (NSCLC).
- Exhibits inhibitory activity against EGFRm/T790M double and EGFRm/T790M/C797S triple mutants.
- Demonstrates potent, robust EGFR pathway inhibition and anti-tumor activity in Osimertinib-resistant models.
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