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Medchemexpress LLC Blu-945 | 2660250-10-0 | 99.6% | C28H37FN6O3S | 10MG
Supplier: Medchemexpress LLC HY14468010MG
BLU-945 is an investigational, next-generation, wild-type-sparing epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor developed for research into treatment-resistant non-small-cell lung cancer. It selectively inhibits activating and resistance EGFR mutants (including T790M and C797S), has demonstrated preclinical and early clinical activity, and is supplied for laboratory research use.
- Potent, selective inhibition of EGFR mutant kinases.
- Spares wild-type EGFR to reduce off-target effects.
- Active against common resistance mutations, including T790M and C797S.
- Orally bioavailable with demonstrated preclinical and early clinical activity.
- Suitable for translational and preclinical studies in EGFR-mutant non-small-cell lung cancer.
- Supplied with high purity and recommended cold, light-protected storage.
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