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Medchemexpress LLC Blu2864 | 2810747-89-6 | 99.5% | 452.43 | 100 MG
Supplier: Medchemexpress LLC HY150076100MG
BLU2864 is an orally active, highly selective, ATP-competitive PRKACA inhibitor with an IC50 of 0.3 nM for PRKACA. It exhibits anti-tumor activity and can be utilized in cancer and polycystic kidney disease research.
- Inhibits forskolin-induced in vitro cystogenesis
- Suppresses renal basal and total PKA activities
- Leads to higher urine outputs and lower kidney weights
- Reduces FLC tumor growth
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