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Selleck Chemical LLC Chk2 Inhibitor II (BML-277) 5mg 516480-79-8
Supplier: Selleck Chemical LLC S86325MG
Chk2 Inhibitor II (BML-277) is an ATP-competitive inhibitor of Chk2 with IC50 of 15 nM. It is 1000-fold more selective toward Chk2 serine/threonine kinase than for Chk1 and Cdk1/B kinases. Chk2 Inhibitor II (BML-277) dose dependently protects human CD4(+) and CD8(+) T-cells from apoptosis due to ionizing radiation. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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