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Enzo Life Sciences BML-278 (25mg). CAS: 15301-69-6
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Supplier:  Enzo Life Sciences BMLGR3590025

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Novel Sirt activator structurally based on a dihydropyridine scaffold. EC150 (effective concentration able to increase enzyme activity by 150%) =1μM for Sirt1 with weaker effect on Sirt2 and Sirt3 (25 and 50μM respectively). The compound is active in whole cells and arrests cell cycle at G1/S phase in U937 cells. Alternative name: N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (5mg/ml). Long Term Storage: Ambient.

Catalog No. 50-201-1007


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