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Enzo Life Sciences BML-283 (25mg)

Supplier: Enzo Life Sciences BMLEI4040025

Potent (AC50 = 0.111µM) and selective (over PKM1, PKR and PKL) activator of the tumor cell specific M2 isoform of pyruvate kinase (PKM2). Pyruvate kinase is a potential target for cancer chemotherapy. A useful new tool for altering aberrant glucose metabolism in cancer cells (Warburg effect). Alternative name: NCGC00030335, 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)-4-(4-methoxyphenylsulfonyl)-piperazine. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (12mg/ml). Long Term Storage: Ambient.
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