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Enzo Life Sciences DL-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol, (10mg), CAS Number: 80938-69-8
Supplier: Enzo Life Sciences BMLSL2100010
Glucosylceramide synthetase inhibitor. Blocks glucosylation of ceramide by inhibiting UDP-glucose:ceramide glucosyltransferase (glucosylceramide synthetase). Inhibits the expression of cell surface glycolipid antigens and inhibits the growth of cultured rabbit skin fibroblasts. Possesses antitumor activity and inhibits Lewis lung carcinoma cell metastasis in vitro. Useful tool for studying the effects of cellular glycosphingolipid depletion. Enhances the apoptotic response to ionizing radiation by enhancing the ceramide signal. Alternative Name: D,L-threo-PDMP. hydrochloride. DL-PDMP. Formula: C23H38N2O3. HCl. MW: 390.6. 36.5. CAS Number: 80938-69-8. Purity: ≥98% (TLC). Appearance: White to off-white solid. Solubility: 25mg/ml soluble in 100% ethanol, DMSO or water (50°C, vortex or sonicate). Use/Stability: Stable for up to 1 year after receipt when stored at -20°C. Solutions are stable for up to 3 months when stored at -20°C. Long Term Storage: -20°C
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