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Medchemexpress LLC BMS-191095 | 166095-21-2 | 98.01% | C22H21ClN4O2 | 50 MG
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Catalog No. 5000353710
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BMS-191095 is a selective activator of mitochondrial ATP-sensitive potassium (mitoKATP) channels. It inhibits human platelet aggregation by opening mitochondrial K(ATP) channels and induces mitochondrial depolarization of vascular smooth muscle cells. It has shown to reduce neuronal damage in animal models of cerebral ischemia.

  • Induces mitochondrial depolarization of vascular smooth muscle cells.
  • Dose-dependently induces vasodilation in endothelium denuded cerebral arteries.
  • Increases the frequency of calcium sparks in vascular smooth muscle cells.
  • Inhibits human platelet aggregation.
  • Reduces neuronal damage in rats with transient focal cerebral ischemia.

Catalog No. 50-003-53710 Supplier Medchemexpress LLC Supplier No. HY1425650MG
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BMS-191095 is a selective activator of mitochondrial ATP-sensitive potassium (mitoKATP) channels. It inhibits human platelet aggregation by opening mitochondrial K(ATP) channels and induces mitochondrial depolarization of vascular smooth muscle cells. It has shown to reduce neuronal damage in animal models of cerebral ischemia.

  • Induces mitochondrial depolarization of vascular smooth muscle cells.
  • Dose-dependently induces vasodilation in endothelium denuded cerebral arteries.
  • Increases the frequency of calcium sparks in vascular smooth muscle cells.
  • Inhibits human platelet aggregation.
  • Reduces neuronal damage in rats with transient focal cerebral ischemia.

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