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Medchemexpress LLC BMS-265246 | 582315-72-8 | C18H17F2N3O2 | 50 MG
SDP

Catalog No. 5000372956
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BMS-265246 is a potent and selective cyclin-dependent kinase (CDK1 and CDK2) inhibitor, with IC50 values of 6 nM and 9 nM, respectively. It inhibits CHI3L1 (chitinase 3-like-1) stimulation of ACE2 (angiotensin converting enzyme 2) and SPP (viral spike protein priming proteases). This product is applicable for ovarian cancer and COVID-19 research, and is intended for research use only.

  • Potent and selective CDK1 inhibitor (IC50: 6 nM)
  • Potent and selective CDK2 inhibitor (IC50: 9 nM)
  • Inhibits CHI3L1 stimulation of ACE2 and SPP
  • Applicable for ovarian cancer research
  • Applicable for COVID-19 research
  • Shows cytotoxic activity in A2780 ovarian cancer cell line (IC50: 0.76 μM)
  • Increases iTreg cell differentiation
  • Prevents E2 induction of EGF3, AREG, and CXCL12 in MCF7 cells
  • Can cooperate with Tamoxifen to induce apoptosis in MCF7 cells

Catalog No. 50-003-72956 Supplier Medchemexpress LLC Supplier No. HY1527550MG
May include imposed supplier surcharges.
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BMS-265246 is a potent and selective cyclin-dependent kinase (CDK1 and CDK2) inhibitor, with IC50 values of 6 nM and 9 nM, respectively. It inhibits CHI3L1 (chitinase 3-like-1) stimulation of ACE2 (angiotensin converting enzyme 2) and SPP (viral spike protein priming proteases). This product is applicable for ovarian cancer and COVID-19 research, and is intended for research use only.

  • Potent and selective CDK1 inhibitor (IC50: 6 nM)
  • Potent and selective CDK2 inhibitor (IC50: 9 nM)
  • Inhibits CHI3L1 stimulation of ACE2 and SPP
  • Applicable for ovarian cancer research
  • Applicable for COVID-19 research
  • Shows cytotoxic activity in A2780 ovarian cancer cell line (IC50: 0.76 μM)
  • Increases iTreg cell differentiation
  • Prevents E2 induction of EGF3, AREG, and CXCL12 in MCF7 cells
  • Can cooperate with Tamoxifen to induce apoptosis in MCF7 cells

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