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Medchemexpress LLC BN82002 hydrochloride | 1049740-43-3 | 99.4% | 395.88 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY112776A50MG

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BN82002 hydrochloride is a potent, selective, and irreversible inhibitor of the CDC25 phosphatase family. It inhibits CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 μM, respectively. The compound demonstrates approximately 20-fold greater selectivity over CD45 tyrosine phosphatase and inhibits cell proliferation in several human tumor cell lines in a concentration-dependent manner in the low micromolar range. Treatment with 50 μM BN82002 modestly affects cell cycle distribution, suggesting cell cycle arrest at various stages.

  • Potent, selective, and irreversible inhibitor of CDC25 phosphatase family.
  • Displays approximately 20-fold greater selectivity over CD45 tyrosine phosphatase.
  • Inhibits cell proliferation in various human tumor cell lines.
  • For research use only.

Catalog No. 50-004-37786


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