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CPC Scientific Boc-Asp(OBzl)-CMK 1MG

Supplier: CPC Scientific CASP022A
Inhibitor that penetrates cells and binds covalently to the active site of caspase-1 (ICE). At a concentration of 2.5 ?M, it blocks caspase-1-mediated processing of mature interleukin-1beta in a monocytic cell line by 85% without influencing tumor necrosis factor processing. ONE-LETTER SEQUENCE: Boc-D(OBzl)-CMKMOLECULAR FORMULA: C17H22Cl1NO5MOLECULAR WEIGHT:355.8STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [172702-58-8], RESEARCH AREA: ApoptosisREFERENCES: N.Boudreau et al., Science, 267, 891 (1995)
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